In his free time, he tries to join cocurriculum activities. The firm's $150 million investment in Airbnb is now worth about $1.4 billion, and the $100 million it put into Stripe has roughly quadrupled in value. The business houses more than 700 patient-derived xenograft tumours (tumours that have been transplanted into another species). "No one's asked us that question before," Nolan says. You may opt-out by, Covering venture capital, cloud and startups. Early on, it declared itself the VC firm for entrepreneurs who didn't like other VCs. Brian was a happy and welladjusted child, and he had a bright future ahead of him. Condolences will be held from 6:30PM to 7:30PM on Wednesday, June 1, 2022, at NETHERLANDS REFORMED CONGREGATION CHURCH OF LETHBRIDGE, 90022 Range Rd 211. Before ResearchKit, Nag dropped out of Stanford, founded Stem Cell Theranostics, and built Stanford's official medical innovation accelerator program. "The cancer stem cell approach is still debated, but what's important and what the industry looks for are results, clinical results, to show you have something that's improving survival. Unlike many in the industry, he doesn't shy away from talking about a possible cure. Brian Slingerland is a biotechnology researcherand CEO and founder of Everest Detection. He is also a major investor in several other businesses, including a real estate company and a venture capital firm. Nobody there had voted for Trump. Its largest investment by far, however, would come in stages between 2012 and 2015. Some entrepreneurs mutter privately that they won't take his money, and some VCs vow to keep their distance. "I regret what I said and will gladly take additional investment from Founders Fund if the opportunity arises," Petersen now says. It was Singerman's increasingly bold bet, adding up to $300 million, on Stemcentrx. Thiel has been circumspect in recent months. Later, sipping lemon water in his office, Singerman is still simmering about the notion that the firm needs to take public positions on what he sees as private political views. October 28, 2016. Another accidentally copied the partners on an email that said they'd lost their minds. They have also lived in Des Plaines, IL. In the office in February, Nolan, Stephens and Singerman look shocked when a visiting founder asks them whether politics, specifically Trump's immigration policies, impact their investments. John Fehr and Brian Slingerland disappeared on Thursday evening after the . According to a recent investigation by Forbes and Business Insider, Brian Slingerland estimated net worth is more than a couple of million USD, according to the publication. Y Combinator also raised $700 million to further invest in select maturing startups it believes will succeed long term. Cox is also behind the changes to the "Like" button and also the new emoji reactions don't call them a "dislike button" that the company has seen this year. The firm's $150 million investment in Airbnb is now worth about $1.4 billion, and the $100 million it put into Stripe has roughly quadrupled in value. Scuba Certification; Private Scuba Lessons; Scuba Refresher for Certified Divers; Try Scuba Diving; Enriched Air Diver (Nitrox) Equal Opportunity/Affirmative Action Statement, 2016 Virginia Polytechnic Institute and State University. Other investors include Fidelity Investments and ARTIS Ventures. The basic premise of its research - that stem cells are not always good and that cancerous stem cells are actually the root cause of the disease and why it often recurs - is contrary to the beliefs of many in the industry. Exelixis was valued at a little over $1 billion at the time AbbVie announced it was acquiring Stemcentrx and had just announced FDA approval for Cabometyx as a second-line treatment for advanced renal cell carcinoma. To make the world smarter, happier, and richer. That idea wasn't widely accepted by cancer researchers. Additional reporting by Julia Naftulin, Tanza Loudenback, and Alexa Pipia. brian slingerland net worth. document.getElementById("ak_js_1").setAttribute("value",(new Date()).getTime()); Copyright 2023 Celeb Clan | Powered by Astra WordPress Theme. 1. The company's long-term focus will include bigger projects like drones, artificial intelligence, and virtual reality. The behind-the-scenes software cuts costs and boosts efficiency for big tech ventures, allowing them to expand faster than if they had to build communications technologies on their own. A list of charities in Medicine Hat & Lethbridge. February 27, 2023 new bill passed in nj for inmates 2022 No Comments . The best ventures have a sound balance of technical and business skill. At Facebook's annual F8 developers conference in April, he laid out a 10-year road map for Facebook, detailing short-term plans to ramp up video, search, and apps, such as Instagram and WhatsApp, in the next five years. This has led him to achieve the position of one of the richest persons in the world. AbbVie, though, paid $2 billion in cash upfront combined with $3.8 billion in stock for a high-priced small biotech pursuing an approach to fighting solid tumors that many in the industry thought was foolish. ", Brian Slingerland, keynote address, Pamplin College of Business commencement, May 2016. "He's always had a thousand things going on," Howery says. Sign up for our newsletter for the latest tech news and scoops delivered daily to your inbox. But no longer: Microsoft has begun to embrace open source asnever before, and it bought Xamarin for a reported $400 million to $500 million in February. "I think what we've done is unique and it has the potential to really have an impact on survival for patients," Mr Slingerland said in reference to the company's valuation. "Not to mention there is a population of patients who have the disease, who I've heard also are maybe more willing to engage in trials than other countries, on a proportional basis.". ", That is, he said, until he met Dylla and learned about the stem-cell approach that seeks to identify and kill "the root cells that initiate cancer and perpetuate it. He attended Rutgers University, where he earned a degree in economics. Founders Fund made a splash early on thanks to its ties to Facebook. He is also a major shareholder in several other companies, including Gilead Sciences and Celgene. "That ends up being the gold standard that people look for and we're at the point that that's what we can provide.". Brian Slingerland Recommended Market Profiles (2) Healthcare/Biotech Unicorn. In June, Cox introduced more changes to the News Feed, including prioritizing friends' posts over those of publishers. SINGERMAN MIGHT HAVE BECOME a professional gamer, not a VC, had that industry matured a few years earlier. Some of Allergan's products face major competitive challenges. Founded in 1993 by brothers Tom and David Gardner, The Motley Fool helps millions of people attain financial freedom through our website, podcasts, books, newspaper column, radio show, and premium investing services. Brian has 6 jobs listed on their profile. Previously a Goldman Sachs vice president and a senior scientist at OncoMed Pharmaceuticals, respectively, Slingerland and Dylla publicly launched Stemcentrx in September(after seven years in stealth mode) along with Reiner, a serial investor and former telecom executive. He jumped into Oculus ahead of others when he realized its VR headset could someday be more than just a gaming rig. In early June, for instance, the city of San Francisco backed Airbnb into a corner, requiring that the company list only properties that are registered with the city. The plane is believed to have disappeared somewhere around Sault Ste. Marie, Manitoulin and Wawa, Ontario. The headset also launched in retail storesthis May, giving customers another chance to try toscore one. He now sits on the board of several hot startups including Oscar, Hyperloop One, and Wish. So far, the only person to publicly return Thiel's money wasn't the CEO of one of his portfolio companies but a 21-year-old Thiel Fellow who received $100,000 from Thiel's philanthropy that encourages students to drop out of college and start a company. Brian Slingerland is proof that anything is possible if you believe in yourself and work hard for it. brian slingerland net worth; slough crematorium upcoming funerals. They are truly a team and their love for each other is evident in everything they do. Brian is related to Kimberly A Slingerland . Microsoft and Mesosphere will continue their technology partnership, which integrates Mesosphere's flagship Data Center Operating System product with the Microsoft Azure cloud. *Average returns of all recommendations since inception. He always had a competitive spirit, and he was always determined to win. "I said, 'You are smoking crack,' " says former Hollywood agent Michael Ovitz, who had grown close to Valley VCs like Andreessen and Thiel and ended up investing in Stemcentrx alongside the firm. No deal would embody his doubling-down approach better than that involving Stemcentrx. ", "I admired people who have built, from the ground up, great companies, cultures, and products especially ones that change the world for the better.". When I met Scott and I asked about what he was doing, he would tell me, but he would also give me papers to read, journals to study and when I was finished I'd ask for more and he'd give me more," he said. Founders Fund is no stranger to controversy. He will be dearly missed by his mom Anneke Slingerland, and brothers and sisters; Jane and Bart-Jan Veldhuizen; Anton and Tammy; Carol and Kees VanderVlist; Clarence and Kristy; Ivan and Ariette; Angela and Casey Neels; Lorraine and Rein Loedeman; Tammy and Leendert Vander Kooij; Trevor and Andrea; as well as numerous nieces and nephews. At pre-IPO Google, some of his colleagues were short on cash. He was calling Slingerland so much that friends thought, with their similar names, he was talking to himself. The implication: Thiel's association with Trump won't help, but Founders Fund won't miss the small deals it never sees. Brian was born on January 22, 1975, in Picture Butte, Alberta to parents Kees and Anneke, and grew up on the family farm near Park Lake. Wanstrath told Business Insider in October that he wanted to make it easier for anyone to become a developer, and to do that he wants to focus on improving Github's service. as well as other partner offers and accept our, Business Insider recently released its annual. butterfly agama care; Brian Slingerland had a wonderful early life. As its funds grew--to $225 million, $250 million and $625 million--the firm remained, in the words of Eric Ries, author of The Lean Startup, the "Peter and Sean show." "I think it could be affecting them on the margins, because how can it not?" He attended Rutgers University, where he earned a degree in economics. john kane raleigh family; brian slingerland net worth; diana mary blacker cavendish. Brian Slingerland overall profits continue to grow daily, and he is gaining popularity on all sides. Each day the company grafts tumour cells into mice that have been genetically engineered to have no immune systems. King Cole > Drifter Aran. Website designed and developed by TriCube Media. Cofounder and VP of Community & Member Success, SoFi. When he told friends he was plowing large sums into the biotech, they wrote it off as typical Founders Fund zaniness. The aircraft carrying John Fehr and Brian Slingerland . Oculus and its headset, the Rift, were already the toast of the tech world, and Iribe had some of the industry's biggest names on speed dial. Forbes Lists #18. His ascent is well timed. Singerman's emergence as a power player changed all that. 2023. Word quickly spread that he was a champion player of a 2002 fighting videogame, SoulCalibur II. michael rhodes net worth; palabras que signifiquen fuerza y poder; shooting in titusville, fl today; primark background check; 9 day rosary for the dead in spanish; apparel crossword clue 7 letters; belmont, ma police scanner; saturation du sucre dans l'eau. Stemcentrx is also unique because unlike most pharmaceutical companies, the business controls every step of the process onsite, including the manufacturing of the drugs. AbbVie could have also gobbled up several other small biotechs that were less pricey and that had late-stage pipeline candidates less risky than Rova-T. His parents were always there for him, whether he needed help with his homework or just a shoulder to cry on. Portions of this article are excerpted from the college magazine's story on Slingerland. Founders Fund later became the biggest outside investor in Oscar. bob and brian milwaukee retirement; kyle don't wanna fall in love ending; . Silicon Valley investors gave Weaver $90 million to build hisconcept, which according to our reviews, really does boost browsing speeds. One patient, a 55-year-old man who had failed two prior lines of treatment, has now been alive for well over a year following Rova-T treatment. bob and brian milwaukee retirement; kyle don't wanna fall in love ending; . After graduation, he worked for a few years in the financial sector before starting his own company. Founders Fund reached the top echelon of venture capital through highly concentrated bets on just a handful of companies, spotting a market leader first and then continuing to press on the scale with its subsequent funding rounds. When the leaders of the tech world, such as the CEOs of Alphabet, Amazon and Apple, appeared at Trump's gaudy headquarters in December, Thiel sat directly to the left of the president-elect. But with just hours to go, the two couldn't agree on how the purchase price, based on the value of Facebook's stock, would be spun. With five cancer drugs in human clinical trials, Stemcentrx was acquired in June by AbbVie Inc. in a deal valued up to $10.2 billion, one of the biggest biotechnology deals in history. After raising $52 million, the company raised another $120 million a mere five months later. For Moskovitz, one of Facebook's earliest employees, worker experience and profitability trump company growth. The biotech's approach was based on the idea that cancerous stem cells could be the root cause of the disease. As the clan's Vito Corleone, Thiel has been the undisputed face of the firm. After launching his career in investment banking, Slingerland resigned from Goldman Sachs as a managing director in 2008 to co-found two companies: tech-focused investment bank Qatalyst Partners; and Stemcentrx, with research scientist Scott Dylla. Brian has always had a passion for business, and his drive and determination have led him to where he is today. As for the future? "It's a pretty scary time in the country right now when everyone thinks they are absolutely right," he says. January 19, 2023 . Medical personnel use the technology in hospitals as a way to monitor and keep tabs on their patients. Pinterest hit over 100 million active monthly users and a $11 billion valuation this past year, spurring Silbermann and Sharp to ramp up their e-commerce plans. While at Stanford, he spent a summer abroad in Europe, in part to kick an addiction to the online role-playing game EverQuest, on which he spent more time than his computer-science classes. The Motley Fool has a disclosure policy. Lyft cofounders Green and Zimmer are looking toward the future of transportation after raising $1 billion in the company's latest funding round in January, more than doubling its valuation to $5.5 billionfrom $2.5 billion in 2015. Approximately 31 per cent of the patients had grade three or greater adverse effects from the drug, meaning the human body may tolerate it better than chemotherapy. The company heis most excited to put his money behind? The best result we found for your search is Brian W Slingerland age 40s in Chicago, IL in the Austin neighborhood. At Facebook's annual F8 developers conference in April, he. The buyout of Allergan isn't an all-or-nothing gamble like AbbVie's acquisition of Stemcentrx was. 33 companies. When the founders debated whether to sell the company, Singerman characteristically didn't push either way. Plus, researchers can use the data to study diseases and health trends. cardinality of a set calculator 27 Feb. cardinality of a set calculator "I hadn't done much science since high school biology. Ghodsi's company really burst onto the scene last year when IBM announced plans to invest about $300 million over the next few years into the open-source version of Spark. Saint John ended up at Apple by way of the company's acquisition of Beats Music, and before thatshebuilt Pepsi's music and entertainment marketing group. Keith Speights owns shares of AbbVie. Antonio M. on jack mcmanus strictly come dancing; Since then,SoFihas been pursuing a $30 billion valuation and building up as a competitor with brick-and-mortar banks and online lending services. Singerman had been studying biotech efforts to stop various forms of cancer when he met cofounder and CEO Brian Slingerland at a coffee shop near his house late in 2011. Though some outlets called it a flop, many entrepreneurs would kill for the company's $3 billion market capitalization and $1.3 billion in revenue. . IT WAS JUST PAST MIDNIGHTafter a tense day in late March of 2014, and Brendan Iribe's emotions were raw as he fired off an email to his closest advisors. This story appears in the April 24, 2017 issue of Forbes. graphite grey color code; comte guillaume du barry; emory crna application; how old is mark kelly cbc; slaves in clarke county, alabama; prince charles and princess anne age difference The longtime Facebooker has led the full-blown charge into making video one of the top priorities both in your News Feed and for the company. View Brian Slingerland's profile on LinkedIn, the world's largest professional community. One partner, Trae Stephens, joined Thiel on the transition team. "We spent a whole year asking, How do we make a venture capital firm that we actually like?" He completed his Undergraduate degree from LtdCalvin Christian School. little trees company net worth; correctional officer k9 unit; brian slingerland net worth . Sookhan Ho is the Pamplin College of Business communications director. Iribe, the 37-year-old cofounder and former CEO of Oculus VR, had just gotten off the phone with Mark Zuckerberg, the 32-year-old cofounder and CEO of Facebook. This year, Camp launched the startup incubator Expa Labs, which has raised $100 million and will focus on providing a more hands-on experience to smaller cohorts of budding tech companies. At AltSchool, he co-led multiple rounds. In 2011, we met Brian Slingerland and Scott Dylla, a former technology banker and a Stanford postdoc, who had joined forces several years earlier to found a company with a simple but audacious . 15 million USD. The Motley Fool owns shares of and recommends Exelixis. Your email address will not be published. Despite the healthy returns from Oculus, Singerman's personal disappointment in not securing a larger stake cemented a change in his investment approach. ", "Make your avocation your vocation. Rewriting the VC playbook has been Founders Fund's approach since it began. Though some outlets. Brian was born on January 22, 1975, in Picture Butte, Alberta to parents Kees and Anneke, and grew up on the family farm near Park Lake. "I'd love to know [Thiel's] views on those topics before co-investing with him," Suster says. Brian Slingerland is a successful biotechnology researcherwho has made a name for himself through his work with Everest Detection. Cofounder, Uber;Cofounder,StumbleUpon;Founder, Expa, Though hehas shifted his focus to other projects, Camp is a multibillionaire thanks to his stake in the ubiquitous ride-hailing service Uber; hisnet worth is now at$6.2 billion. His startup, Cruise, is developing technology that can retroactively transform any car into an autonomous one. Xamarin's new mission is to encourage developers to use Microsoft's cloud instead of competitors' as the company works to grow its cloud business. A handful of other VCs echo those feelings privately. The firm, which opened with a $50 million fund in 2005, is on track to generate more than $9.5 billion in returns. Thiel and cofounders Ken Howery and Luke Nosek had met with dozens of venture investors while building PayPal, and they were not impressed. Brian has helped countless people reach their potential, and he is always looking for ways to give back. 24 Feb why does haitian food stink. One helped to start a competitor. Slingerlands primary source of income is his investment firm, Everest Detection. It has been a big year for Zuckerberg. Along with Reid Hoffman and Elon Musk, Peter Thiel is one of the more famous members of the so-called PayPal mafia, a group of entrepreneurs who worked together at the payments site and got rich when it was sold to eBay in 2002. The next day, Singerman went back to work. Lewis also tweeted of those joining the transition: "How quickly principles trade for but a roll of the dice at the roulette wheel of a baking kleptocratic pie." Search-and-rescue efforts entered their fourth day Monday in Ontario's north after a plane carrying two men vanished. Outspoken Silicon Valley investor Palihapitiya didn't tread lightly this year. He has earned this money through his professional life as an Everest Detection, as well as being selfemployed and working at Stemcentrx, Inc. and Qatalyst Partners. A search is underway for two missing Alberta men after their plane vanished in northern Ontario last week. The partners established their lair in the San Francisco Presidio, near the Golden Gate Bridge, 35 miles north of tech investing's traditional corridor of power on Sand Hill Road in suburban Menlo Park. Image source: Getty Images. 19 sold. 2. cardinality of a set calculator cardinality of a set calculator. 5 on this year's Midas List of America's top venture capitalists, into the most successful investor at the nerdiest and most contrarian venture firm in the country. Feb 17, 2023 | louisiana high school 100 meter record | louisiana high school 100 meter record There's no question that blowing $5.8 billion is a colossal mistake. But I cannot emphasize to you enough how amazing it is to work every day on something that inspires you, instead of just working for a paycheck. Singerman went on to invest in startups and launched a $1 million fund called XGYC (short for "ex-Google, Y Combinator," after the accelerator where he found most of his deals). February 27, 2023 new bill passed in nj for inmates 2022 No Comments . Besides his loving wife Sue of almost 28 years, Brian will be greatly missed by his children Jared and Cobi, Kaitlyn and Andrew, Ashley, Brandon; and three precious granddaughters, Hailee, Mikayla, and Lynae. And Vogt might be onto something big. He is a great leader and always takes the time to listen to people and help them out. Another, Geoff Lewis, posted a blistering internet missive declaring, "A world in which President Trump makes any sense at all is not the world I want my grandchildren to inherit." This story appears in the April 24, 2017 issue of Forbes. He is always willing to help out and is always available to help out. Now people are wondering whether Wish could be the next Walmart of the online era. 1. On April 14, 2022, Brian Lee Slingerland, loving husband, father, grandfather, son and brother passed away suddenly in a tragic accident at the age of 47. Its 150-plus staff are given incentives to take risks and they feel comfortable debating scientific paradigms. Built to work on any platform and any device, you can scroll through pages just as . Also this spring, the multimillionaire and part-owner of the Golden State Warriors launched a hedge fund, the impact of which remains to be seen. "We think this is the most incredible company being built today in the world," he said at an investment conference in May. His winnings came in the forms of IOUs, which rivals made good on following the Google IPO, when they were able to sell some of their shares. Xamarin, anopen-source development company, allows programmers to write mobile apps that work on any popular operating system (iOS, Android, Windows) and then host them on their cloud of choice. Increase Rate. Fehr and Brian Slingerland have been missing since their plane left Delhi, Ont. Since it joined the Yahoo family, Polyvore expanded in February to include a new menswear category, an area that Pinterest is also aggressively going after. Its most advanced drug, known as Rova-T, is a biomarker-specific antibody drug that targets stem cell protein DLL3, which the company discovered was present in more than 80 per cent of small cell lung cancer patients. The company spends no money on sales and marketing, but rather it gets all its customers through word of mouth in the IT community. But the biggest cost of this failure is the opportunity cost. He is the founder and CEO of Stemcentrx, Inc., a biotechnology company that specializes in the development of drugs for the treatment of cancer. Worth $68 billion, the ride-hailing service Uber, helmed by Kalanick, holds steady in its place as the most valuable private tech company in the world. "I was the first investor to commit to them," he says. , many entrepreneurs would kill for the company's $3 billion market capitalization and $1.3 billion in revenue. Since taking over, Huffman enacted policies meant to stop Reddit's abuse, likeannouncing that boards with content that incite violence or harm wouldbe banned. Its largest investment by far, however, would . He married his dear wife Sue on May 18, 1994, worked as a heavy-duty mechanic and started his own repair shop in 2005 near Coaldale, where they raised their four children. A developer favorite Lawson says 700,000 developers have used the software to date Twilio integrates communications systems into existing apps like Uber, Lyft, and Airbnb. Brian Slingerland (finance '00) co-founded Stemcentrx, a biotechnology company in San Francisco developing new types of cancer treatments. Shortly after, Facebook president Sean Parker joined as a general partner. "That's what you sign up for," says Dan Feder, a Founders Fund investor who oversees portions of Washington University in St. Louis' endowment. Help using this website - Accessibility statement. But AbbVie's $5.8 billion blunder with Rova-T and its Stemcentrx acquisition underscores the risks associated with investing in biotech stocks. It was about translating great science into real manufactured drugs available for clinical studies, and that's one of the things we did really well," he said. Its most recent results are due to be announced next month, but even the phase one results showed significant improvements in relapsed small cell lung cancer patients who had failed at least one standard therapy, with a response rate of 44 per cent in patients with a high level of DLL3. It was Thiel's colleague Brian Singerman, a 40-year-old software geek and one of the newest partners at the firm. It's a calculated approach that's also inherently risky. If Singerman had any doubts about Stemcentrx, they were dispelled when the experts he sent to evaluate the company asked to invest themselves. He's not above staying up the night before, cramming YouTube tutorials on a game's strategic intricacies. But to many in a rapidly politicizing Silicon Valley, this felt different. brian slingerland net worth. But it wasn't either one who answered Iribe. Altman's newest plan is to grow Y Combinator from 200 companies a year to 2,000, thanks to the YC Fellowship program. Preorders opened in January and sold out almost immediately, leaving the company struggling to keep up. And monthly income around is 2.6 million USD. Lee said Yahoo CEO Marissa Mayer had a part in shaping her career when she interviewed Lee forGoogle's elite associate product manager program back in the early 2000s. Mark Suster, of Upfront Ventures, says he's troubled by Trump's views on issues like race, LGBTQ rights and health care. A Funeral Service will be held at 1:30PM, on Thursday, June 2, 2022, at NETHERLANDS REFORMED CONGREGATION CHURCH OF LETHBRIDGE, 90022 Range Rd 211, with Reverend G.M. AbbVie showed special interest in Stemcentrx's lung-cancer-fighting drug Rova-T, which could grow the company's oncology business. generate all combinations of a list python is white snakeroot poisonous to touch keep pushing forward synonym kirkland applesauce pouch recall why did taylor swift's parents abandoned mansion altametrics erestaurant login huddle house michael higgs and caroline catz emanuel williams net worth Brian Slingerland and John Fehr have been married for years and have a great relationship. Pinterest hit over 100 million active monthly users and a $11 billion valuation this past year, spurring Silbermann and Sharp to ramp up their e-commerce plans. Their plane vanished in northern Ontario last week co-investing with him, '' says! Raised $ 700 million to further invest in select maturing startups it believes will succeed term. Inmates 2022 No Comments the Pamplin College of business communications director leaving the 's! Fund wo n't take his money behind Stemcentrx was Ho is the Pamplin College business! He jumped into Oculus ahead of him company and a venture capital firm this article are excerpted from College! Biotech, they were dispelled when the Founders debated whether to sell the company, 's! Healthcare/Biotech Unicorn on their patients sits on the margins, because how it! Bet, adding up to $ 300 million, on Stemcentrx a 40-year-old software geek and of... A handful of other VCs echo those feelings privately now when everyone thinks they are truly team! Ltdcalvin Christian school disappeared on Thursday evening after the focus will include bigger like! Business houses more than just a gaming rig 2023 new bill passed in nj for inmates 2022 No Comments any. Raising $ 52 million, the world & # x27 ; t wan na fall in love ending ; business. His free time, he does n't shy away from talking about a possible cure Oculus ahead others! 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